BioContext7

BioContext7

Bioinformatics registry aggregator and self-healing pipeline generator for Claude Code

BioContext7 unifies 25,000+ tools from bio.tools, nf-core, and Bioconda into a single searchable index with EDAM semantic annotations. It generates production-ready pipelines in Nextflow, Snakemake, and WDL from natural language descriptions, with LSP-validated self-healing loops that automatically fix errors.

How It Works

User: "Create an RNA-seq pipeline"
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BioContext7:
1. Queries registries (bio.tools, nf-core, Bioconda)
2. Resolves EDAM ontology → tool chain
3. Compiles to Nextflow/Snakemake/WDL
4. Validates with LSP → auto-fixes errors
5. Runs stub tests → verifies execution
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Output: Production-ready pipeline

Key Features

  • 25k+ tools from bio.tools with EDAM semantic search
  • Self-healing pipelines — LSP validation + automatic error correction
  • Multi-target compilation — Nextflow DSL2, Snakemake, WDL
  • MCP Server — integrate directly with Claude Code
  • Pipeline composition — chain tools by input/output compatibility
  • GA4GH Standards — Beacon, VRS, Phenopackets, WES integration
  • Protein databases — UniProt sequence and annotation retrieval
  • Metabolomics — HMDB, Metabolomics Workbench, MassBank, LIPID MAPS

Registry Coverage

CategoryRegistryCoverageClient
Bio Toolsbio.tools25,000+ toolsBioToolsClient
ContainersBioContainersContainer imagesBioContainersClient
OntologyEDAMSemantic termsEDAMOntology
ProteinUniProtSequences, annotationsUniProtClient
GenomicsGA4GH BeaconFederated variantsBeaconClient
GenomicsGA4GH VRSVariant IDsVRSClient
GenomicsGA4GH WESWorkflow executionWESClient
MetabolomicsHMDB220,000+ metabolitesHMDBClient
MetabolomicsMetabolomics Workbench4,200+ studiesMetabolomicsWorkbenchClient
MetabolomicsMassBankMass spectraMassBankClient
MetabolomicsLIPID MAPSLipid structuresLipidMapsClient

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